Primary investigator
Kasper Krommes - kasper.krommes@regionh.dk
Senior researchers
Per Hölmich og Kristian Thorborg
Study team members
Mathias Fabricius Nielsen, Frederikke Villumsen, Amalie Bjerre Jørgensen, Jesper Larsen, Sylvi Henriette Strømme, Kathrine Tang Møller, Caroline Bardrum, Nicoline Kousgaard-Laursen, Mia Cecilie Pedersen, Tore Madsen, Julie Eggertsen Rørth, Cecilie Haugaard Høy.
Collaborators
Prof. Michael Skovdal Rathleff, Amalie Bjerre, Prof. Jens Lykkegaard-Olesen, Biostatistican Thomas Kallemose, Senior Associate Prof. Mikkel Bek Clausen.
Purpose of the study/project
Osgood-Schlatter affects 1 in 10 adolescents and causes anterior knee pain and physical inactivity. No level 1 evidence exists to guide conservative treatment for Osgood-Schlatter. This trial investigates if a standardized self-management approach would demonstrate superior effectiveness over usual care for 10–16-year-olds with Osgood-Schlatter for improving self-reported knee function.
About the study/project
The most cited works on Osgood-Schlatter are mainly narrative reviews, case reports, and retrospective case-series, while no high-level evidence supports current conservative management approaches. This is likely in part due to the prevalent notion of Osgood-Schlatter as a self-limiting condition, making the development of new treatments seem unwarranted. Current care reflects this, with clinicians and patients reporting varied and conflicting advice and modalities being utilized. Recent systematic reviews call for evidence on conservative approaches which is likely further hindered by the unique challenges of conducting high-quality trials in pediatric populations. A recent cohort study found positive short and long-term changes in knee function and pain in a smaller group of adolescents with Osgood-Schlatter, following a novel self-management approach. This novel approach provided adolescents and parents with tools to self-manage the condition through education, exercises, and activity modification, but it is unknown if this intervention is superior to usual care.
Funding
Fond for forskning, kvalitet og uddannelse i fysioterapipraksis: DKK 678.200
Østifterne: DKK 599.958
Helsefonden: DKK 350.000
Købmand Ferdinand Salling Mindefond: 219.000
Fond for Frie Forskningsmidler, Hvidovre Hospital: DKK 100.000
Beckett Fonden: DKK 70.000
Frimodt-Heinke Fond: DKK 50.000
FLS Industries A/S Gavefond: DKK 50.000
Danish Society of Sports Physical Therapy: DKK 25.000 & 6.000
Link to protocol