The SELECT Trial

​The effect of arthroscopic subacromial decompression in patients with subacromial impingement syndrome who are non-responders to non-operative treatment. A patient- and assessor-blinded, randomized, controlled trial. 

Primary investigator ​

Adam Witten 

Senior researchers 

Kristoffer W. Barfod, Per Hölmich, Kristian Thorborg


​University, Department of Midwifery, Physiotherapy, Occupational Therapy and Psychomotor Therapy, Faculty of Health, University College Copenhagen

About the study/project

Subacromial impingement syndrome (SIS) is one of the most common causes of shoulder pain, and it poses a large socioeconomic burden. Non-operative treatment is considered first line of treatment, but many patients experience unsatisfactory results from this. If non-operative treatment fails, arthroscopic subacromial decompression (ASAD) might be considered, but RCT’s, comparing ASAD to investigational shoulder arthroscopy indicate that ASAD might only provide limited therapeutic effect, if any at all. The existing evidence does not support the current use of ASAD, but it has been argued that the RCT’s findings cannot be generalized to all patients with SIS, especially those who clearly does not benefit from non-operative treatment. Therefore, it is not known if ASAD still should be considered a last resort for patients with stalling or worsening symptoms in response to sufficiently tried non-operative treatment.

Purpose of the study/project​​​​

To investigate if glenohumeral arthroscopy and ASAD is more effective than glenohumeral arthroscopy alone in improving patient-reported outcome at 12 months in patients with SIS who are non-responders to non-operative treatment​. Identifier


​Funded by: 

Amager og Hvidovre Hospitals Forskningsfond ​​

Responsible editor