Medication

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Background

Medication in the older population is a complex field. The aging process is associated with physiological changes such as a decrease in hepatic clearance, a decrease in glomerular filtration capacity, loss of total muscle mass and impaired homeostatic mechanisms. These changes have an impact on the pharmacodynamics and –kinetics, which increases the risk of adverse drug reactions in older people. 

Medication for the older population is becoming a noticeable problem as the average life expectancy is increasing. The prevalence of older persons with multiple (chronic) diseases, increases the chance of poly-pharmacy. Further, older persons are frequently admitted to hospitals; this increases the complexity of handling drugs to older people between the primary and secondary sector. 

Main Focus 

Our main focus has been on Potentially Inappropriate Medications (PIMs), which are drugs which carry more risks than benefits for older people. PIMs and poly-pharmacy expose older people to a greater risk of adverse drug reactions. 

Further we have looked at the implementation of Shared Medication Card (in Danish: KMK - Fælles Medicin Kort), which is a new computer system to handling medicine. 

​Finished studies 

Potentially inappropriate medication related to weakness in older acute medical patients. Jensen, L. D., Andersen, O., Hallin, M. & Petersen, J. 11 apr 2014 I : International Journal of Clinical Pharmacy. 36, 3, s. 570-580 

Implementering af fælles medicinkort er vanskeligt. Christensen, S., Jensen, L. D., Kaae, S., Vinding, K. L. & Petersen, J. 21 jul 2014 I : Ugeskrift for Laeger. 176, 15, s. 1389-1391

Medical Amputees and their Medical Treatment. Title in Danish: Medicinske Amputationspatienter og deres lægemiddelbehandling. Ditte Carlsen Lehtonen og Julie Sejersbøl Nielsen [Master Thesis] University of Copenhagen, Completion date: 1. september 2015​

Medications related to hospital readmissions among older medical patients - a qualitative and quantitative study. Title in Danish: Lægemidler relateret til genindlæggelse hos ældre medicinske patienter - et kvalitativt.og kvantitativt studie. Maria Raahauge Herborg Bay og Simone Renée Jensen [Master Thesis] University of Copenhagen, Completion date: 14. april 2014

Problems Using FMK at Discharge Seen From a Hospital Doctors’ Perspective. Title in Danish: Problemer ved brugen af det Fælles Medicinkort (FMK) ved udskrivelse set fra hospitalslægers perspektiv. Selina Christiansen [Master Thesis] University of Copenhagen, Completion date: 14. September 2012
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