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Cancer (eng.)

Cancer Research

Cancer affects 25.000 Danes annually, which means that one Dane is diagnosed with cancer every 10 minutes.

Heredity colorectal cancer
Cancer Research at the Clinical Research Centre, Hvidovre Hospital, focuses at the 10-15% of colorectal cancer that develop because of heredity. The national hereditary nonpolyposis colorectal cancer (HNPCC) registry at Hvidovre Hospital, which was established in 1991, constitutes a powerful resource for studies of hereditary colorectal cancer and other cancer types linked hereto.

Individuals with hereditary cancer generally develop tumors at young age and are at increased risk of multiple primary malignancies. Hereditary cancer also affects the family, since also family members may be at increased risk.

Our research within hereditary colorectal cancer focuses at genomic tumor profiles and psychosocial consequences.


Our studies

Array-based technologies are applied to generate complete tumor profiles where expression patterns can be linked to gains and losses and further validated using e.g. immunostaining in tissue microarray based tumor series. This approach aims at identifying genes linked to hereditary colorectal cancer development and to recognize genetic profiles of diagnostic and predictive importance. Genotype-phenotype correlations are investigated with the aim to refine future diagnostics and risk estimates.

The psychosocial studies investigate long-term effects of hereditary cancer - in particular the experiences from young adults and the impact on family relations. Standardized research instruments are applied in order to identify individuals in need of support with the aim to develop individualized psychosocial follow-up.

Seniorforsker i cancer, se her.